28 research outputs found

    Performance Study of Cryptography based Dynamic Multi-Keyword Searchable Security Algorithm in Cloud Using CRSA /B+ Tree

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    Today, Cloud computing is a buzz word in IT industry. Cloud, a shared pool of computing resources, allows access to needed resources on demand through internet and web applications. Since data is outsourced to third party, user needs to maintain the accountability of their data in cloud. Hence preserving the confidentiality and securing the sensitive data in cloud is a major concern. Many cryptographic techniques have been proposed by researchers to assure the confidentiality of the user2019;s data in cloud. But, the challenging task is to provide the secure search over this preserved data which has been encrypted so as to retrieve the effective data. Hence, we are proposing a system to have a secure search over the encrypted data on the cloud which preserves its confidentiality. In our system, a noble approach has been made using the Commutative-RSA algorithm, a cryptographic technique where the dual encryption takes place thus reducing the overall computation overhead. The search operation over the encrypted data is based on the tree search algorithm which supports multi-keyword search. Based on the relevance score, the more appropriate data is retrieved on the search operation. Using this approach, the information is not leaked when the encrypted data is searched by users and also the queries are handled in an efficient way. Finally, we demonstrate the effectiveness and efficiency of the proposed schemes through extensive experimental evaluation

    Concerted Regulation of cGMP and cAMP Phosphodiesterases in Early Cardiac Hypertrophy Induced by Angiotensin II

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    Left ventricular hypertrophy leads to heart failure and represents a high risk leading to premature death. Cyclic nucleotides (cAMP and cGMP) play a major role in heart contractility and cyclic nucleotide phosphodiesterases (PDEs) are involved in different stages of advanced cardiac diseases. We have investigated their contributions in the very initial stages of left ventricular hypertrophy development. Wistar male rats were treated over two weeks by chronic infusion of angiotensin II using osmotic mini-pumps. Left cardiac ventricles were used as total homogenates for analysis. PDE1 to PDE5 specific activities and protein and mRNA expressions were explored

    Intermittent Hypoxia-Induced Cognitive Deficits Are Mediated by NADPH Oxidase Activity in a Murine Model of Sleep Apnea

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    Background: In rodents, exposure to intermittent hypoxia (IH), a hallmark of obstructive sleep apnea (OSA), is associated with neurobehavioral impairments, increased apoptosis in the hippocampus and cortex, as well as increased oxidant stress and inflammation. Excessive NADPH oxidase activity may play a role in IH-induced CNS dysfunction. Methods and Findings: The effect of IH during light period on two forms of spatial learning in the water maze and well as markers of oxidative stress was assessed in mice lacking NADPH oxidase activity (gp91phox _/Y) and wild-type littermates. On a standard place training task, gp91phox _/Y displayed normal learning, and were protected from the spatial learning deficits observed in wild-type littermates exposed to IH. Moreover, anxiety levels were increased in wild-type mice exposed to IH as compared to room air (RA) controls, while no changes emerged in gp91phox _/Y mice. Additionally, wild-type mice, but not gp91phox _/Y mice had significantly elevated levels of NADPH oxidase expression and activity, as well as MDA and 8-OHDG in cortical and hippocampal lysates following IH exposures. Conclusions: The oxidative stress responses and neurobehavioral impairments induced by IH during sleep are mediated, at least in part, by excessive NADPH oxidase activity, and thus pharmacological agents targeting NADPH oxidase may provid

    A Survey on Data Association Methods in VSLAM

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    Abstract In robotics the Simultaneous Localization and Mapping (SLAM

    Synthesis and biological activity of some 3-methyl/ethoxycarbonyl-6- arylimidazo[2,1<i>-b</i>]thiazoles and their 5-bromo/5-formyl derivatives

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    393-398Facile reaction of arylacylbromide 1 with 2-amino-4- methylthiazole 2 and its hindered reaction with 2-amino-4-ethoxycarbonylthiazole 3 during the synthesis of 3-methyl/ethoxycarbonyl-6-aryl imidazo[2,1-b] thiazoles 8/9 are explained on the basis of electronic effects of the 4-substituent of thiazole substrate. Their bromination/formylation afforded the corresponding 5-bromo and 5-formyl derivatives . Results of preliminary screening of the target compounds reveal moderate anthelmintic and anti-inflammatory activity
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